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Medchemexpress LLC Tspo ligand-1 | 4560-08-1 | C16H10ClNO2 | 5 MG
Supplier: Medchemexpress LLC HY1504075MG
TSPO ligand-1 is the ligand of AUTAC4 that can be used in the synthesis of PROTACs. It is a mitochondrial outer membrane transmembrane structural domain protein that binds to AUTAC4, regulating mitochondrial autophagy to promote targeted mitochondrial renewal. It also plays a role in cholesterol transport and serves as a sensitive biomarker of brain injury and neurodegeneration.
- Gene expression is increased with selective neuron activation.
- Can serve as a marker of glial cell activity in Alzheimer's disease.
- Regulates mitochondrial fatty acid oxidation (FAO).
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