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Apexbio Technology LLC TTP 22 329907-28-0 10mg
SDP

Supplier:  Apexbio Technology LLC A389410

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TTP 22 (CAS 329907-28-0) is a potent ATP-competitive inhibitor of casein kinase 2 (CK2) exhibiting an IC50 of 0 1 M and a Ki of 40 nM CK2 is a constitutively active serine/threonine kinase involved in the phosphorylation of a broad array of cellular substrates influencing diverse signaling pathways implicated in oncogenesis inflammation and viral infections Kinetic analyses attribute TTP 22 s high affinity for CK2 to its thieno[2 3-d]pyrimidin-4-ylthio carboxylic acid moiety which competitively binds the ATP pocket In vitro profiling indicates notable selectivity for CK2 over several other kinase families TTP 22 serves as a valuable tool compound for investigating CK2-mediated cellular processes in disease research

Catalog No. 50-000-95443


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