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Selleck Chemical LLC Tucatinib
Supplier: Selleck Chemical LLC S8362100MG
Tucatinib (Irbinitinib ONT-380 ARRY-380) is an oral potent selective reversible and ATP-competitive small-molecule inhibitor of ErbB-2 (also called HER2) with IC50s of 8 nM and 7 nM for ErbB-2 and p95 HER2 respectively in cell-based assays showing 500-fold selective for HER2 vs EGFR It has potential antineoplastic activity
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