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Medchemexpress LLC Tunicamycin | 11089-65-9 | 99.9% | 844.94 | C39H64N4O16 | 10 MG
Supplier: Medchemexpress LLC HYA009810MG
Tunicamycin is a mixture of homologous nucleoside antibiotics that inhibits N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT), causing accumulation of unfolded proteins in the endoplasmic reticulum and inducing ER stress. It is used in research to study the unfolded protein response, glycoprotein synthesis, and related cell cycle effects.
- Inhibits N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT).
- Induces ER stress and activates the unfolded protein response.
- Reported antimicrobial and anti-cancer activities in the literature.
- Off-white to light yellow solid with high reported purity.
- Soluble in DMSO, water (requires pH adjustment), and ethanol; in vivo formulations described.
- Powder storage: -20°C (long-term); in solvent: -80°C (months) or -20°C (short-term).
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