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Medchemexpress LLC Tyloxapol | 25301-02-4 | 10 G
Supplier: Medchemexpress LLC HYB106810G
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, functioning as a surface active stabilizer. It is utilized to induce hyperlipidemia in animals, characterized by high levels of plasma triglycerides and LDL-cholesterol, and reduced HDL-cholesterol. It can increase plasma cholesterol levels by promoting hepatic cholesterol synthesis and disturbing lipolytic enzymes, blocking lipid uptake from circulation.
- Used to induce hyperlipidemia in animals
- Triggers detachment of HEK293 cells
- Induces nuclear fragmentation and apoptotic nuclei
- Increases risk of pulmonary hemorrhage and causes cytotoxicity
- Reduces AChE and MAO enzyme activities in rat plasma and brain
- Leads to reduction in plasma urea, creatinine, and bilirubin
- Appearance: liquid
- Color: colorless to light yellow
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