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Medchemexpress LLC Tyrphostin AG 879 | 148741-30-4 | 99.3% | 316.46 | 100 MG
Supplier: Medchemexpress LLC HY20878100MG
This compound is a tyrosine kinase inhibitor that specifically acts on TrKA phosphorylation and also functions as a selective ErbB2 tyrosine kinase inhibitor. It demonstrates significantly higher selectivity for ErbB2 compared to EGFR. This agent exhibits anticancer properties by reducing cell proliferation and inducing apoptosis in various cell lines, and has shown to decrease tumor growth in animal models.
- Inhibits TrKA phosphorylation.
- Selective ErbB2 tyrosine kinase inhibitor.
- Exhibits at least 500-fold higher selectivity to ErbB2 than EGFR.
- Possesses anticancer activity.
- Decreases cell proliferation in various cell lines.
- Induces apoptosis in multiple cell lines.
- Reduces tumor growth in athymic, immunodepressed mice.
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