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Medchemexpress LLC Tyrphostin AG1296 | 146535-11-7 | MFCD00270913 | 99.69% | 266.29 | 100 MG
Supplier: Medchemexpress LLC HY13894100MG
Tyrphostin AG1296 is a potent and selective inhibitor of platelet-derived growth factor receptor (PDGFR), inhibiting signaling of human PDGF α- and β-receptors, and the stem cell factor receptor (c-Kit). It is also an inhibitor of FLT3. It has a purity of 99.69%.
- Potent and selective inhibitor of PDGFR
- Inhibits human PDGF α- and β-receptors
- Inhibits stem cell factor receptor (c-Kit)
- Potent inhibitor of FLT3
- Suppresses viability of PLX4032-resistant melanoma cells
- Induces apoptosis of A375R cells
- Inhibits PDGFR phosphorylation
- Inhibits migration of A375R cells
- Suppresses A375R tumor growth in nud/nud mice
- Inhibits atherosclerotic plaque progression
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