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Apexbio Technology LLC UC2288 1394011-91-6 1mL(10 mM in DMSO)
Supplier: Apexbio Technology LLC BA34565.1
UC2288 (CAS 1394011-91-6) is a cell-permeable orally bioavailable small molecule structurally derived from sorafenib It selectively downregulates p21 expression at the mRNA level independent of p53 status resulting in reduced p21 protein levels with minimal impact on protein stability UC2288 does not inhibit VEGFR2 or kinase activity even at concentrations up to 10 M This compound is utilized in biomedical research to investigate the cellular functions of p21 and its regulatory pathways and to explore potential therapeutic strategies targeting p21-associated mechanisms
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