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ABclonal Technology UCP3 Rabbit pAb
Supplier: ABclonal Technology A15321000UL
Mitochondrial uncoupling proteins (UCPs) are part of the mitochondrial anion carrier protein (MACP) family. They uncouple oxidative phosphorylation from ATP synthesis, dissipating energy as heat, known as the mitochondrial proton leak. UCPs transfer anions across the mitochondrial membrane and reduce the mitochondrial membrane potential. The expression of UCPs varies by tissue; this gene is primarily expressed in skeletal muscle. Its protein product is believed to protect mitochondria from lipid-induced oxidative stress. When fatty acid supply exceeds oxidation capacity, UCP facilitates the export of excess fatty acids from mitochondria. UCPs contain three solcar protein domains typical of MACPs. Two splice variants of this gene have been identified.
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