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ATCC UCSF-OT-1109 (ATCC CRL-3442) Human Oral Tongue Squamous Cell Carcinoma Cell Line - Frozen, Adherent, Epithelial-like
Supplier: ATCC CRL3442
UCSF-OT-1109 (ATCC CRL-3442) is a human oral tongue squamous cell carcinoma (OTSCC) cell line supplied frozen for cancer research and molecular studies. The line is adherent with epithelial-like morphology, has documented karyotype and oncogenic alterations, and is suitable for 3D culture and translational oncology research.
- Human oral tongue squamous cell carcinoma model derived from a 44-year-old female never-smoker.
- Adherent, epithelial-like cells suitable for 3D cell culture and oncology research.
- Supplied frozen for long-term storage in liquid nitrogen vapor.
- Grows in DMEM supplemented with 10% fetal bovine serum; population doubling time approximately 4-5 days.
- Characterized karyotype with chromosome number ranging from 75 to 88.
- Documented oncogenic alterations include CDKN2A, TP53, SPTBN5, NOTCH2, and FAM136A.
- Biosafety level 1, appropriate for handling in standard laboratory facilities.
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