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Cayman Chemical UK 122trIfluoROCTAte salt 10mg
SDP

Supplier:  Cayman Chemical 900121810 MG

Encompass_Preferred

An SMG1 inhibitor (IC50 0.11 nM) selective for SMG1 over mTOR Cdk1 Cdk2 PI3Ka and PI3KY (IC50s 0.05 32 7.1 0.092 and 0.06 UM respectively) and a panel of 25 additional kinases (IC50s >10 UM) but does inhibit GSKa and GSKB (IC50s 0.26 and 0.33 UM respectively) decreases the phosphorylation of the SMG1 substrate UPF1 in MDA-MB-361 cells from 0.3-3 UM inhibits the proliferation of MDA-MB-468 cells (IC50 0.075 UM)

Catalog No. 50-289-2758


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