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ABclonal Technology ULBP1 Rabbit mAb
Supplier: ABclonal Technology A2116120UL
The protein encoded by this gene is a ligand of natural killer group 2 member D (NKG2D) an immune system-activating receptor on NK cells and T-cells Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways including those of JAK2 STAT5 ERK and PI3K kinase Akt Also in cytomegalovirus-infected cells this ligand binds the UL16 glycoprotein and is prevented from activating the immune system Three transcript variants encoding different isoforms have been found for this gene
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