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Medchemexpress LLC Ulefnersen sodium | 2589926-27-0 | 98.47% | 7060 (free acid) | 1 MG
Supplier: Medchemexpress LLC HY147410A1MG
Ulefnersen sodium (ION363) is an Antisense Oligonucleotide (ASO) that targets the 6th intron of the fused-in sarcoma (FUS) transcript to silence FUS in a non-allele-specific manner.
- Reduces postnatal levels of FUS protein in the brain and spinal cord
- Delays motor neuron degeneration in disease-relevant mouse models of ALS-FUS
- Used in the research of Amyotrophic Lateral Sclerosis (ALS)
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