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Medchemexpress LLC UNC-2170 50mg | 1648707-58-7 | 50 MG
Supplier: Medchemexpress LLC HY11553150MG
UNC-2170 is a fragment-like small-molecule ligand for 53BP1, a methyl-lysine reader protein involved in DNA damage response. It binds 53BP1 with micromolar affinity and is used as a biochemical probe for studying 53BP1 interactions and function.
- Functionally active fragment-like ligand for 53BP1.
- Binds 53BP1 with Kd = 22 μM and inhibits with IC50 = 29 μM.
- Shows at least 17-fold selectivity for 53BP1 versus other methyl-lysine reader proteins.
- Molecular weight 313.23; formula C14H21BrN2O.
- Available as solid powder or as DMSO solution for biochemical assays.
- Recommended storage: solid at 4°C; solutions at -80°C (up to 6 months) or -20°C (up to 1 month).
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