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Medchemexpress LLC Urea, N-(2,4-dibromophenyl)-N'-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]- | 708275-58-5 | 99.2% | 484.18 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY10896

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JNJ-10397049 is a potent and selective orexin 2 receptor (OX2R) antagonist with a pKi of 8.3, exhibiting 600-fold selectivity for OX2R over OX1R. It is intended for research use only.

  • Potent and selective orexin 2 receptor (OX2R) antagonist
  • 600-fold selective for OX2R over OX1R
  • Decreases latency for persistent sleep and increases nonrapid eye movement and rapid eye movement sleep time
  • Blocks ethanol self-administration, place preference, and reinstatement
  • Suitable for oral and intraperitoneal injection protocols

Catalog No. 50-003-47276


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