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Medchemexpress LLC Urea, N-butyl-N'-(10,11-dihydro-10-methyl-11-oxodibenzo[b,f]thiazepin-8-yl)- | 891509-95-8 | 98.0% | 355.45 | 5 MG
SDP

Supplier:  Medchemexpress LLC 5MGHY111952

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SR-4995 is a highly effective and selective ligand for α-β-hydrolase domain-containing 5 (ABHD5). It facilitates the activation of adipose triglyceride lipase (ATGL) by displacing ABHD5 from its inhibitory regulators. SR-4995 directly interacts with ABHD5, promoting lipolysis in adipocytes and muscle tissues while circumventing PKA-dependent signaling pathways.

  • Highly effective and selective ligand for α-β-hydrolase domain-containing 5 (ABHD5).
  • Facilitates activation of adipose triglyceride lipase (ATGL).
  • Displaces ABHD5 from inhibitory regulators, perilipin-1 (PLIN1) and PLIN5.
  • Directly interacts with ABHD5, inhibiting its association with PLIN1.
  • Promotes lipolysis in adipocytes and muscle tissues.
  • Circumvents PKA-dependent signaling pathways.

Catalog No. 50-003-64429


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