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Selleck Chemical LLC URMC-099
SDP

Supplier:  Selleck Chemical LLC S734310MM/1ML

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URMC-099 is an orally bioavailable brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM 42 nM 14 nM and 150 nM for MLK1 MLK2 MLK3 and DLK respectively and also inhibits LRRK2 activity with IC50 of 11 nM URMC-099 also inhibits ABL1 with IC50 of 6 8 nM URMC-099 induces autophagy

Catalog No. 50-000-04298


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