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Medchemexpress LLC Urotensin II (114-124), human (TFA) | 251293-28-4 | 99.8% | 1502.59 | 10 MG

Supplier: Medchemexpress LLC HYP1164A10MG
Urotensin II (114-124), human, is an 11-amino acid residue peptide that acts as a potent vasoconstrictor and agonist for the orphan receptor GPR14. It is intended for research use only.
- 11-amino acid residue peptide.
- Potent vasoconstrictor.
- Agonist for the orphan receptor GPR14.
- Binds to recombinant human GPR14 with high affinity, functionally coupled to calcium mobilization.
- Induces concentration-dependent increases in intracellular calcium in HEK-293 cells expressing human GPR14 (EC50=0:62±0.17 nM).
- Markedly increases total peripheral resistance in anesthetized non-human primates, associated with cardiac contractile dysfunction.
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