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Cayman Chemical UtreglutIde 10mg
Supplier: Cayman Chemical 4127510 MG
A G protein-biased peptide agonist of GLP-1R; selectively induces cAMP accumulation in HEK293 cells expressing human GLP-1R over β-arrestin recruitment in CHO-K1 cells expressing human GLP-1R (EC50s = 0.63 and 79 nM, respectively); induces insulin secretion in INS-1 832/3 cells (EC50 = 6.3 nM); reduces food intake and body weight, increases plasma insulin levels, and decreases plasma glucose, HbA1c, glucagon, and triglyceride levels in diabetic db/db mice from 1.5-6 nmol/kg
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