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Medchemexpress LLC UZH2 50mg | 2756566-45-5 | 50 MG
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Supplier:  Medchemexpress LLC HY11571750MG

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UZH2 is a potent, selective small-molecule inhibitor of the RNA methyltransferase METTL3 for laboratory research use. It exhibits a biochemical IC50 of 5 nM and reduces m6A levels in cells, with reported cellular EC50 values of 0.7 μM (MOLM-13) and 2.5 μM (PC-3). The compound is supplied as a high-purity solid suitable for biochemical and cell-based studies.

  • Potent METTL3 inhibition: biochemical IC50 5 nM.
  • Cellular activity: reduces m6A/A ratio (MOLM-13 EC50 0.7 μM; PC-3 EC50 2.5 μM).
  • High purity: 98.9%.
  • Provides molecular data (formula, weight, SMILES) for cheminformatics and assay design.
  • For research use only; not for human or clinical use.

Catalog No. 50-002-27811


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