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Apexbio Technology LLC Vadadustat 1000025-07-9 50mg
Supplier: Apexbio Technology LLC B796050
Vadadustat (CAS 1000025-07-9) is an orally bioavailable inhibitor of hypoxia-inducible factor prolyl-hydroxylase (HIF-PH) modulating cellular oxygen-sensing pathways By inhibiting HIF-PH enzymes vadadustat stabilizes hypoxia-inducible factors leading to increased endogenous erythropoietin production and subsequent stimulation of erythropoiesis This mechanism offers an alternative to traditional erythropoiesis-stimulating agents in the management of anemia associated with chronic kidney disease (CKD) especially in patients receiving maintenance dialysis Vadadustat is utilized in biomedical research to explore oxygen-sensing regulation erythropoiesis and novel therapeutic strategies for CKD-related anemia
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