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Apexbio Technology LLC Valaciclovir HCl 124832-27-5 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B20615.1
Valaciclovir HCl is an orally bioavailable hydrochloride ester prodrug of the antiviral nucleoside analog acyclovir It is designed to selectively inhibit viral DNA polymerase thereby disrupting herpesvirus DNA synthesis and replication Valaciclovir HCl exerts its biological activity primarily through rapid conversion to acyclovir which is phosphorylated first by viral thymidine kinase and then by cellular kinases to form acyclovir triphosphate This metabolite selectively inhibits viral DNA polymerase Based on these pharmacological properties Valaciclovir HCl holds research potential in exploring antiviral mechanisms and investigating pharmacological pharmacokinetic and resistance aspects associated with herpesvirus infections
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