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Apexbio Technology LLC Valinomycin 2001-95-8 25mg
Supplier: Apexbio Technology LLC B738825
Valinomycin (CAS 2001-95-8) is a small-molecule potassium ionophore targeting potassium ion transport It is designed to facilitate selective potassium ion translocation across lipid membranes thereby disrupting intracellular potassium homeostasis Valinomycin exerts its biological activity primarily through passive transport of potassium ions leading to mitochondrial membrane depolarization and induction of apoptotic pathways In in vitro studies using Chinese hamster ovary (CHO) cells valinomycin induces apoptosis within 12 hours of exposure with an IC50 value around or below 1 M in cell-based assays Based on these pharmacological properties valinomycin holds research potential in studies of mitochondrial-mediated apoptosis and ion homeostasis
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