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Medchemexpress LLC Vardenafil | 224785-90-4 | 99.8% | 200 MG
SDP

Supplier:  Medchemexpress LLC HYB0442200MG

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Vardenafil is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. It shows inhibitory effects towards PDE1 and PDE6 with IC50s of 180 nM and 11 nM, respectively, while its IC50s are >1000 nM for PDE3 and PDE4. Vardenafil works by competitively inhibiting cyclic guanosine monophosphate (cGMP) hydrolysis, thereby increasing cGMP levels.

  • Potent and selective PDE5 inhibitor
  • Increases cGMP levels through competitive inhibition
  • Can be used for research of erectile dysfunction
  • Can be used for research of hepatitis
  • Can be used for research of diabetes

Catalog No. 50-004-05444


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