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Medchemexpress LLC Vasculotide | 1359657-45-6 | 99.8% | 14000 (average) | 1 MG
Supplier: Medchemexpress LLC HYP105801MG
Vasculotide is an angiopoietin-1 mimetic that acts as a Tie-2 activator, inducing Tie-2 phosphorylation. It has anti-inflammatory and anti-permeability effects. This product ameliorates endotoxin-induced endothelial barrier dysfunction, promotes angiogenesis in a mouse model of diabetic ulcer, protects mice from vascular leakage, reduces mortality in murine abdominal sepsis, decreases microvascular leakage, and improves microcirculatory perfusion in a rat model of hemorrhagic shock.
- Acts as a Tie-2 activator
- Induces Tie-2 phosphorylation
- Exhibits anti-inflammatory effects
- Exhibits anti-permeability effects
- Ameliorates endothelial barrier dysfunction
- Promotes angiogenesis
- Protects from vascular leakage
- Reduces mortality in abdominal sepsis
- Decreases microvascular leakage
- Improves microcirculatory perfusion
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