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Medchemexpress LLC Vebicorvir | 2090064-66-5 | 99.7% | 467.44 | 10 MM 1 ML
Supplier: Medchemexpress LLC HY109195200MG
Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor. It suppresses covalently closed circular DNA (cccDNA) formation in two de novo infection models with EC50s ranging from 1.84 μM to 7.3 μM. In vitro, it inhibits pgRNA, HBeAg, and HBsAg production, and is also an inhibitor of pgRNA encapsidation and rcDNA synthesis. The product appears as a white to off-white solid for research use only.
- Suppresses covalently closed circular DNA (cccDNA) formation
- Inhibits pgRNA, HBeAg, and HBsAg production
- Inhibits pgRNA encapsidation and rcDNA synthesis
- Appears as a white to off-white solid
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