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Medchemexpress LLC VH285-PEG4-C4-Cl (HaloPROTAC 3) | 1799506-07-2 | ≥98.0% | 799.42 | 50 MG

Supplier: Medchemexpress LLC HY11199750MG
VH285-PEG4-C4-Cl (HaloPROTAC 3) is a conjugate of ligands for E3 and a 16-atom-length linker. This degrader incorporates the VH285 based VHL ligand and an alkyl/ether-based linker.
- Highly potent and efficacious degrader of GFP-HaloTag7 with a DC50 of 19 nM.
- Able to induce 90% degradation of GFP-Halotag at 625 nM.
- Binds to VHL with an IC50 of 0.54 μM.
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