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Medchemexpress LLC Vinblastine sulfate | 143-67-9 | MFCD08706468 | 99.9% | 1 ML

Supplier: Medchemexpress LLC HY1378010MM/1ML
Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. It inhibits microtubule formation and suppresses nAChR with an IC50 of 8.9 μM. It strongly blocks mitosis, leading to cell death by apoptosis, and has an antiproliferative effect by inducing apoptosis through Bax/Bcl-2 imbalance and by suppressing NFκB expression.
- Inhibits microtubule formation
- Suppresses nAChR (IC50: 8.9 μM)
- Blocks mitosis and induces apoptosis
- Antiproliferative effect
- Suppresses NFκB expression
- Triggers apoptosis via mitochondrial membrane potential loss and caspase activation
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