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Medchemexpress LLC Vincristine-d3-ester sulfate | 1217854-24-4 | 926.05 | 1 MG
Supplier: Medchemexpress LLC HYN0488S11MG
Vincristine-d3-ester (sulfate) is a deuterium-labeled Vincristine sulfate, an antitumor vinca alkaloid that inhibits microtubule formation in mitotic spindles. This action causes dividing cells to arrest at the metaphase stage by binding to microtubules with a Ki of 85 nM. Deuterium substitution can affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Inhibits microtubule formation in mitotic spindles.
- Leads to metaphase arrest in dividing cells.
- Used in research to study drug pharmacokinetics and metabolism.
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