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Medchemexpress LLC Vorasidenib 25mg | 1644545-52-7 | 25MG
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Supplier:  Medchemexpress LLC HY10404225MG

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Vorasidenib (AG-881) is an orally available brain penetrant second-generation dual mutant isocitrate dehydrogenases 1 and 2 (mIDH1/2) inhibitor Vorasidenib (AG-881) exhibits nanomolar inhibition of (D)-2-hydroxyglutarate (D-2-HG) and the IC50 ranges of 0 04 22 nM against IDH1 R132C IDH1 R132G IDH1 R132H and IDH1 R132S and 7 14 nM against IDH2 R140Q and 130 nM against IDH2 R172K Vorasidenib can be used for the study of grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1/2 mutation[1 [2

Catalog No. 50-002-43587


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