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Medchemexpress LLC Voriconazole | 137234-62-9 | 99.5% | C16H14F3N5O | 5 MG
SDP

Supplier:  Medchemexpress LLC HY762005MG

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Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent. It inhibits fungal ergosterol biosynthesis by inhibiting 14-α-lanosterol demethylation, a process mediated by fungal cytochrome P450 enzymes. It is also capable of penetrating the blood-brain barrier (BBB).

  • Inhibits fungal ergosterol biosynthesis.
  • Inhibits 14-α-lanosterol demethylation.
  • Penetrates the blood-brain barrier.
  • Active against *S. apiospermum* (MIC 0.5 μg/mL) and *C. neoformans* (MIC 0.125-0.25 μg/mL).
  • Disrupts fungal cell membranes and halts growth.

Catalog No. 50-004-34188


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