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Apexbio Technology LLC VRT-1353385 1616113-45-1 5mg
Supplier: Apexbio Technology LLC B58965
VRT-1353385 (CAS 1616113-45-1) is a small-molecule antagonist targeting the chemokine receptor CCR9 It is designed to inhibit CCR9 thereby modulating immune cell homing to the intestinal mucosa and regulating lymphocyte migration and accumulation within gut tissue VRT-1353385 exerts its biological activity primarily through selective CCR9 antagonism In cell-based studies VRT-1353385 demonstrates inhibition of CCR9-mediated cell migration with an IC50 value of approximately 5 9 nM Based on these pharmacological properties VRT-1353385 holds research potential in the prevention of recurrence of postoperative Crohn s Disease
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