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Medchemexpress LLC Vu 0365114 | 1208222-39-2 | 99.4% | 397.35 g·mol⁻1 | C22H14F3NO3 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY107651100MG

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VU 0365114 is a small-molecule selective positive allosteric modulator of the muscarinic acetylcholine receptor M5 for research use. It potentiates acetylcholine-stimulated responses in cellular assays and has been reported to increase insulin secretion in human β-cells. Reported potency is micromolar with minimal activity at M1-M4.

  • Selective mAChR M5 positive allosteric modulator with EC50 ~1.6-2.7 μM.
  • Demonstrated increase of acetylcholine-stimulated insulin secretion in human β-cells.
  • High purity approximately 99.4%.
  • Solid, light yellow to orange appearance.
  • Molecular formula C22H14F3NO3; molecular weight 397.35 g·mol⁻1.
  • Powder stable at -20°C for extended storage.

Catalog No. 50-002-42176


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