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Abcam VU0155041 sodium salt, PAM for mGluR4, 10MG
Supplier: Abcam AB12024810MG
MW 338.2 Da, Purity >98%. Positive allosteric selective modulator at mGluR4 (EC50 values are 798 and 693 nM at human and rat mGluR4 receptors, respectively). It has advantages over PHCCC (ab120043) as it is water soluble and more potent. Shows limited blood-brain barrier permeability. Active in behavioural models of Parkinson's disease following icv injection. Also available in simple stock solutions (ab146686) - add 1 ml of water to get an exact, ready-to-use concentration.
The product is subject to the following: Abcam Restricted Use Statement
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