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Cayman Chemical VU0357017hydrochlorIde 10mg
SDP

Supplier:  Cayman Chemical 1193910 MG

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A selective agonist of M1 mAChRs (Ki = 9.91 µM); selective for M1 over M2-M5 mAChRs (Kis = 21.4-50 µM in CHO cells); increases calcium mobilization and activates the ERK signaling pathway (EC50 = 1.6 and 37 µM, respectively, in CHO cells expressing human recombinant M1 receptors); reverses scopolamine-induced deficits in contextual fear conditioning in rats (10 mg/kg)

Catalog No. 50-295-3298


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