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Medchemexpress LLC WAY-600 | 1062159-35-6 | C28H30N8O | 2 MG
Supplier: Medchemexpress LLC HY152722MG
WAY-600 is a potent, ATP-competitive, and selective mTOR inhibitor. It blocks mTOR complex 1/2 (mTORC1/2) assembly and activation, exhibiting concentration and time-dependent inhibition of HepG2 and Huh-7 cell viability. It also inhibits BrdU incorporation and increases caspase-3 and caspase-9 activity in HepG2 cells, and inhibits HepG2 tumor growth in nude mice.
- Potent, ATP-competitive, and selective mTOR inhibitor.
- Blocks mTOR complex 1/2 (mTORC1/2) assembly and activation.
- Inhibits HepG2 and Huh-7 cell viability.
- Decreases HepG2 cell colonies and inhibits BrdU incorporation.
- Increases caspase-3 and caspase-9 activity.
- Inhibits HepG2 tumor growth in nude mice.
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