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Medchemexpress LLC WNK-IN-11-d3 | 2123483-49-6 | 99.8% | 465.41 | 10 MG

Supplier: Medchemexpress LLC HY112094S10MG
WNK-IN-11-d3 is an orally active, selective, and potent With-No-Lysine (WNK) kinase inhibitor. It is effective at regulating cardiovascular homeostasis. This compound can be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Orally active, selective, and potent WNK kinase inhibitor
- Regulates cardiovascular homeostasis
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Improves rat PK profile, including lower clearance and enhanced oral bioavailability
- Significantly reduces systolic blood pressure in mice
- Induces dose-dependent diuresis, natriuresis, and kaliuresis
- Reduces blood pressure, stroke volume, and total peripheral resistance; increases heart rate
- Efficacious in rodent models of hypertension and volume overload
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