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Medchemexpress LLC N-[4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]pyrrolidine-2-carboxamide | 945755-56-6 | MFCD24386874 | 99.7% | 444.53 | C25H28N6O2 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY137755MG

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XL019 is a potent, orally bioavailable, selective inhibitor of Janus kinase 2 (JAK2) with low-nanomolar enzymatic potency and demonstrated cellular activity against JAK2-driven signaling.

  • Potent JAK2 inhibition (IC50 ≈ 2.2 nM) with weaker activity against JAK1 and JAK3.
  • Inhibits STAT3 and STAT5 phosphorylation in cells expressing mutant or wild-type JAK2.
  • High chemical purity (≈99.7%) suitable for research applications.
  • Molecular weight 444.53 and formula C25H28N6O2.
  • Soluble in DMSO (≈25 mg/mL); use fresh DMSO and ultrasonic assistance if needed.
  • Solid, light yellow to green yellow appearance; supplied as a 5 mg quantity.
  • Recommended storage: powder -20°C for long-term; in solution -80°C.

Catalog No. 50-208-1508


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