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Medchemexpress LLC XP-524 | 2344825-52-9 | 98.02% | 552.65 | 1 ML
Supplier: Medchemexpress LLC HY14700810MM/1ML
XP-524 is a potent BET and EP300 inhibitor that shows great tumoricidal activity in vivo. It prevents KRAS-induced neoplastic transformation and extends survival in aggressive PDAC mouse models. XP-524 also enhances the presentation of self-peptide and tumor recruitment of cytotoxic T lymphocytes, making it a potential research tool for pancreatic ductal adenocarcinoma (PDAC).
- Potent BET and EP300 inhibitor
- Exhibits significant tumoricidal activity in vivo
- Prevents KRAS-induced neoplastic transformation
- Prolongs survival in aggressive PDAC mouse models
- Enhances self-peptide presentation
- Promotes tumor recruitment of cytotoxic T lymphocytes
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