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Medchemexpress LLC XVA143 | 264275-77-6 | 905576 | 99.9% | 562.36 | 25 MG
Supplier: Medchemexpress LLC 25MGHY139202
XVA143 is an α/β I-like allosteric antagonist that inhibits LFA-1 dependent firm adhesion while simultaneously enhancing adhesion in shear flow and rolling both in vitro and in vivo. It is intended for research use only.
- Inhibits LFA-1 dependent firm adhesion
- Enhances adhesion in shear flow and rolling
- Completely abolishes binding of ICAM-1 to LFA-1
- Restores rolling of αL-E310A β2 mutant
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