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Medchemexpress LLC YAP-TEAD-IN-1 TFA | 1659305-79-9 | 99.99% | 2133.88 | 5 MG
Supplier: Medchemexpress LLC HYP2244A5MG
YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of YAP-TEAD interaction, demonstrating an IC50 of 25 nM. This 17mer peptide is characterized by its higher binding affinity to TEAD1 (Kd=15 nM) compared to YAP (50-171) (Kd= 40 nM). It functions by inhibiting the interaction between YAP and TEAD, key proteins involved in cell proliferation and organ size regulation.
- Potent and competitive peptide inhibitor
- Inhibits YAP-TEAD interaction with an IC50 of 25 nM
- 17mer peptide structure
- Higher binding affinity to TEAD1 (Kd=15 nM) than to YAP (50-171) (Kd= 40 nM)
- Impacts cell proliferation and organ size regulation
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