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Medchemexpress LLC YKL-06-062 | 2172617-16-0 | 99.4% | 50 MG
SDP

Supplier:  Medchemexpress LLC HY12914150MG

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YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC50 of 2.12 nM/1.40 nM/2.86 nM for SIK1, SIK2 and SIK3, respectively. It increases MITF mRNA expression in a dose-dependent manner (0.0004-16 μM; 3 hours) in human melanocyte cells and UACC62 melanoma cells.

  • Second-generation salt-inducible kinase (SIK) inhibitor
  • Exhibits IC50 of 2.12 nM/1.40 nM/2.86 nM for SIK1, SIK2 and SIK3
  • Increases MITF mRNA expression in a dose-dependent manner
  • Tested in human melanocyte cells and UACC62 melanoma cells

Catalog No. 50-003-40409


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