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Medchemexpress LLC YKL-06-062 | 2172617-16-0 | 99.4% | 50 MG

Supplier: Medchemexpress LLC HY12914150MG
YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC50 of 2.12 nM/1.40 nM/2.86 nM for SIK1, SIK2 and SIK3, respectively. It increases MITF mRNA expression in a dose-dependent manner (0.0004-16 μM; 3 hours) in human melanocyte cells and UACC62 melanoma cells.
- Second-generation salt-inducible kinase (SIK) inhibitor
- Exhibits IC50 of 2.12 nM/1.40 nM/2.86 nM for SIK1, SIK2 and SIK3
- Increases MITF mRNA expression in a dose-dependent manner
- Tested in human melanocyte cells and UACC62 melanoma cells
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