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Cayman Chemical YM-298198hydrochlorIde 10mg
Supplier: Cayman Chemical 2292510 MG
A non-competitive antagonist of mGluR1 (Ki = 19 nM); selective for mGluR1 over mGluR2-7 (IC50s = 0.016 and >10 μM, respectively); increases nociceptive response latency in a mouse model of streptozotocin-induced hyperalgesia (10 and 30 mg/kg, p.o.); reduces reinstatement of drug-seeking behavior induced by cocaine priming in rats
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