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Medchemexpress LLC YSK 05 | 1318793-78-0 | 98.68% | 628.07 | 1 ML
Supplier: Medchemexpress LLC HY14708710MM/1ML
YSK 05 is a pH-sensitive cationic lipid that enhances the intracellular trafficking of non-viral vectors. It is notable for its ability to overcome the suppression of endosomal escape caused by PEGylation and effectively enhances siRNA delivery both in vitro and in vivo. YSK 05 facilitates the endosomal escape of MEND, thereby improving the efficacy of siRNA delivery into the cytosol and enhancing gene silencing.
- Enhances intracellular trafficking of non-viral vectors
- Exhibits significant gene silencing activity and hemolytic activity
- Overcomes suppression of endosomal escape by PEGylation
- Effective in enhancing siRNA delivery both in vitro and in vivo
- Used for research purposes in areas like oligonucleotides, cationic lipids, and drug delivery
- Related to cancer research, including cancer metabolism and metastasis
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