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Medchemexpress LLC Yx968 | 2742732-92-7 | 98.06% | 831.12 | 50 MG
Supplier: Medchemexpress LLC HY16423350MG
YX968 is a potent and selective HDAC3/8 PROTAC dual degrader that exhibits antitumor activity by promoting apoptosis. It consists of a target protein ligand, a linker, and an E3 ligase ligand.
- Induces cell apoptosis by blocking G1 phase
- Cleavage of CASP3 was induced in a dose-dependent manner
- Targets HDAC3 with a DC50 of 1.7 nM
- Targets HDAC8 with a DC50 of 6.8 nM
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