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Medchemexpress LLC Z-val-ala-asp | 162852-62-2 | 99.8% | 437.44 | 5 MG
Supplier: Medchemexpress LLC HY1643885MG
Z-VAD is an irreversible, broad-spectrum pan-caspase inhibitor that can inhibit a variety of caspases. It blocks apoptosis signaling pathways, induces autophagy and necrosis in tumor cells, and exhibits anti-angiogenic activity. It can also enhance the sensitivity of breast cancer and lung cancer cells to radiotherapy in vitro and in vivo, prolonging the growth delay of tumor xenograft models. Z-VAD is well tolerated and is primarily used in research concerning cancer radiosensitization and cell death pathway regulation.
- Inhibits a variety of caspases
- Blocks apoptosis signaling pathways
- Induces autophagy and necrosis in tumor cells
- Has anti-angiogenic activity
- Enhances sensitivity of breast and lung cancer cells to radiotherapy
- Prolongs growth delay of tumor xenograft models
- Well tolerated
- Mainly used in research related to cancer radiosensitization and cell death pathway regulation
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