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Cayman Chemical Zileuton, 111406-87-2, 10 mg

Supplier: Cayman Chemical 1000696710

Molecular Formula C11H12N2O2S, Purity >98%, Formula Weight 236.3, Synonyms: A 64077; Zileuton is a reversible 5-LO inhibitor that was approved in 1997 for the prevention and treatment of asthma in the USA, but was withdrawn by Abbott Laboratories in 2003.{1367,13304} Zileuton inhibits 5-LO from rat basophilic leukemia-1 (RBL-1) cells with an IC50 value of 0.5 M. It is a potent inhibitor of LTB4 production in purified human peripheral blood polymorphonuclear leukocytes (PMNL) with an IC50 value of 0.6 M.{1367}
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