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Medchemexpress LLC Zinc phthalocyanine | 14320-04-8 | 98.0% | 577.90 | 5 G
Supplier: Medchemexpress LLC HY192045G
Zinc phthalocyanine (ZnPc) is commonly applied in industry as catalysts and photoconductors, and in biomedical fields for photodynamic therapy (PDT). It can be used to photooxidise cyclohexane and is promising for research in solar-cell applications.
- Inhibits the growth of cancer cells Kyse-140 and OE-33 with IC50 values of 1.41 μM and 3.35 μM respectively (1-10 μM, 24 h).
- Acts as a photosensitizer that is taken up by cancer cells and produces Reactive Oxygen Species (ROS) under specific wavelength light irradiation (694 nm).
- Impairs mitochondrial membrane integrity, activates caspase-3, and induces apoptosis.
- Causes long-term damage to the microvascular network of the CAM (10 μM, topical application, single dose).
- Exhibits antitumor activity in chick chorioallantoic membrane models.
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