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Medchemexpress LLC Zxh-4-130 TFA | 2711006-67-4 | 99.7% | C48H59F3N6O11S | 10MG
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Supplier:  Medchemexpress LLC HY132857A10MG

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ZXH-4-130 TFA is a hetero-PROTAC trifluoroacetate salt that selectively induces degradation of cereblon (CRBN) by recruiting the VHL E3 ligase. It has demonstrated ~80% CRBN degradation at 10 nM in MM1.S cells and is supplied as a solid research reagent for investigating targeted protein degradation and CRBN-related biology.

  • Selective degradation of cereblon (CRBN) at low nanomolar concentrations.
  • Hetero-PROTAC mechanism recruiting VHL E3 ligase for targeted ubiquitination.
  • Demonstrated cellular activity in MM1.S cells for assay validation.
  • High reported purity suitable for research applications.
  • Solid form with recommended -20°C sealed storage to preserve stability.
  • Intended for use in studies of protein degradation pathways and target validation.

Catalog No. 50-002-58213


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