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Filtered Search Results
Medchemexpress LLC Val-cit-PAB-OH | 159857-79-1 | MFCD 22381209 | 99.6% | 379.45 g/mol | C18H29N5O4 | 5 G
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Val-cit-PAB-OH is a protease-cleavable antibody-drug conjugate (ADC) linker that combines a valine-citrulline dipeptide with a para-aminobenzyl (PAB) self-immolative spacer. It is designed to release cytotoxic payloads inside target cells following lysosomal protease cleavage, and is supplied as a high-purity solid for conjugation chemistry and linker optimization.
- Protease-cleavable Val-Cit dipeptide for intracellular release.
- Para-aminobenzyl self-immolative spacer enabling clean payload liberation.
- High reported purity suitable for conjugation workflows.
- Well-characterized chemical formula and molecular weight for analytical planning.
- Available in multiple package sizes to support discovery and scale-up.
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STA PHARMACEUTICAL US LLC Fmoc-L-Val-L-Pro-OH | 1 g | CAS 109425-49-2 | MDL MFCD00237675
Fmoc-L-Val-L-Pro-OH is a Amino Acid reagent (Subcategory: Val) sold by WuXi TIDES. Offered in 1 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 109425-49-2
- MDL: MFCD00237675
- InChIKey: PNFSGKNIZOXLKU-VXKWHMMOSA-N
- Molecular Weight: 436.508
- Molecular Formula: C25H28N2O5
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29339980
- Country Of Origin: China
- IUPAC: (((9H-fluoren-9-yl)methoxy)carbonyl)-L-valyl-L-proline
- SMILES: CC([C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(N4CCC[C@H]4C(O)=O)=O)C
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STA PHARMACEUTICAL US LLC Fmoc-(Fmoc-Hmb)-Val-OH | 100 g | CAS 148515-86-0 | MDL MFCD00278816
Fmoc-(Fmoc-Hmb)-Val-OH is a Amino Acid reagent (Subcategory: Val) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 148515-86-0
- MDL: MFCD00278816
- InChIKey: SEBWBBFTTQDBSZ-FAIXQHPJSA-N
- Molecular Weight: 697.784
- Molecular Formula: C43H39NO8
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: N-(((9H-fluoren-9-yl)methoxy)carbonyl)-N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)oxy)-4-methoxybenzyl)-L-valine
- SMILES: CC([C@H](N(C(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)CC4=C(OC(OCC5C6=CC=CC=C6C7=CC=CC=C75)=O)C=C(OC)C=C4)C(O)=O)C
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Medchemexpress LLC Val-cit-amide-ph-maytansine | 98.0% | 1055.61 | C51H71ClN8O14 | 10 MG
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Val-Cit-amide-Ph-Maytansine is a maytansine-derived small molecule intended for use as an antibody-drug conjugate (ADC) payload or linker component. It is supplied as a powder for formulation and conjugation studies and includes solubility and storage guidance for research handling.
- Val-cit-amide-ph-maytansine is a maytansine-derived ADC linker-payload.
- Purity is approximately 98.01%.
- Molecular weight 1055.61 and formula C51H71ClN8O14.
- Supplied as a powder with recommended storage at -20°C (long term) and 4°C (short term).
- Highly soluble in DMSO (100 mg/mL) and compatible with recommended in vivo formulations.
- Available in small research sizes (1 mg, 5 mg, 10 mg, 25 mg, 50 mg, larger sizes by quote).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Fmoc-Val-Cit-PAB-PNP | 863971-53-3 | MFCD22200278 | 99.6% | 766.80 | C40H42N6O10 | 1 G
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Fmoc-Val-Cit-PAB-PNP is a protease-cleavable antibody-drug conjugate (ADC) linker containing a valine-citrulline dipeptide and a p-aminobenzyl (PAB) self-immolative spacer; enzymatic cleavage releases carbamate-linked payloads for intracellular delivery.
- Contains Val-Cit dipeptide and p-aminobenzyl (PAB) spacer.
- Cleavable by lysosomal proteases such as cathepsin B.
- Enables enzymatic release of carbamate-linked payloads.
- Demonstrates high plasma stability compared with non-cleavable linkers.
- Supplied with high purity (99.6%).
- Available in milligram to gram scales for development and synthesis workflows.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC DMBA-SIL-Mal-MMAE | 2923885-49-6 | 1403.65 | 25 MG
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DMBA-SIL-Mal-MMAE is a cytotoxin-linker conjugate for ADC with potent antitumor activity. It uses the anti-mitotic agent monomethyl auristatin E (MMAE, a tubulin inhibitor), linked to DMBA-SIL-Mal. It is for research use only and not for sale to patients.
- Cytotoxin-linker conjugate for ADC
- Potent antitumor activity
- Uses anti-mitotic agent monomethyl auristatin E (MMAE, a tubulin inhibitor)
- Linked DMBA-SIL-Mal
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Medchemexpress LLC Mc-d-val-d-cit-pab-pnp | 1350456-68-6 | MFCD22200431 | 98.8% | 737.76 | C35H43N7O11 | 5 MG
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A protease-cleavable peptide linker used for synthesizing antibody-drug conjugates (ADCs). The linker contains a Val-Cit dipeptide and a para-nitrophenyl (PNP) leaving group, providing enzymatic payload release after internalization. Intended for research use only.
- Cleavable Val-Cit dipeptide linker.
- Maleimide-compatible conjugation handle for payload attachment.
- PNP leaving group for facile conjugation chemistry.
- High purity with analytical data (COA, HNMR, LCMS, RP-HPLC).
- Available in multiple small pack sizes for research workflows.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Fmoc-Val-Ala-OH 25g
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Fmoc-Val-Ala-OH is a reagent consisting of a Val-Ala dipeptide with an Fmoc protecting group on its N-terminus Carboxylic acids can be reactive with alcohols or amines while the Fmoc protecting group can be removed with piperidine to allow for coupling with carboxylic acids to form amides
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Medchemexpress LLC Fmoc-NMe-Val-Val-Dil-Dap-OH | 1352202-13-1 | 96.2% | 807.03 | C45H66N4O9 | 500 MG
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Fmoc-NMe-Val-Val-Dil-Dap-OH is an Fmoc-protected peptide intermediate used to build drug-linker conjugates for antibody-drug conjugate (ADC) research. Supplied as a solid powder for research use, the compound is characterized by molecular formula C45H66N4O9, molecular weight 807.03, and a reported supplier purity of ~96.2%.
- Fmoc-protected peptide intermediate suitable for linker synthesis.
- Intended for preparation of drug-linker conjugates used in ADC construction.
- Supplied as a solid powder for laboratory handling and storage.
- Molecular weight 807.03 and formula C45H66N4O9 to support formulation planning.
- Reported high purity suitable for research applications.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC SuO-Val-Cit-PAB-MMAE | 99.2% | 1264.51 g/mol | C63H97N11O16 | 100 MG
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SuO-Val-Cit-PAB-MMAE is a drug-linker conjugate for antibody-drug conjugate research that links the antimitotic payload monomethyl auristatin E (MMAE) to a protease-cleavable SuO-Val-Cit-PAB peptide linker, enabling intracellular release of the cytotoxic payload. The compound is supplied as a solid reagent for use as a building block in ADC synthesis and preclinical studies.
- Protease-cleavable SuO-Val-Cit-PAB linker for targeted payload release.
- Contains monomethyl auristatin E (MMAE) as the cytotoxic payload.
- High purity suitable for research applications.
- DMSO soluble; dissolve with ultrasonic and warming as needed.
- Stored under inert atmosphere at -80°C to preserve stability.
- Supplied in multiple package sizes for research flexibility.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Val-cit-PAB-OH | 159857-79-1 | MFCD22381209 | 99.6% | 379.45 g/mol | C18H29N5O4 | 100 MG
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Val-cit-PAB-OH is a protease-cleavable, degradable antibody-drug conjugate (ADC) linker (valine-citrulline-p-aminobenzyl alcohol) supplied as a white to off-white solid for research use. It is designed for incorporation into ADCs to enable payload release following enzymatic cleavage and is provided with supporting documentation including a datasheet, certificate of analysis, and safety data sheet.
- Degradable protease-cleavable linker enabling controlled payload release.
- Suitable for ADC synthesis and linker-drug conjugation workflows.
- High purity appropriate for research applications.
- Soluble in DMSO at ≥ 100 mg/mL for preparation of concentrated stocks.
- Stable when stored at 4°C under inert atmosphere; in solution, store at -80°C for long-term storage.
- Supplied as a white to off-white solid for handling and formulation flexibility.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Biotium Amine Reactive Dyes Reactive CF Dyes Other Dyes Biotinylation Reagents Reactive CF Dyes CF505 1/EA
CF Dye Succinimidyl Esters (SE NHS esters) are Biotiums next-generation fluorescent dyes in amine-reactive form for labeling antibodies and other proteins CF505 is a green-fluorescent STORM-compatible dye that is structrually equivalent to ATTO 488 Ex/Em 505/519 nm 1 umol per vial
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eMolecules 15891-50-6 | Ac-Nva-OH | Combi-Blocks | MFCD00151963 | 159.185 | C7H13NO3 | 98.000 | CCC[C@H](NC(C)=O)C(O)=O | 5g | 117563712
Ac-Nva-OH | Combi-Blocks | 15891-50-6 | MFCD00151963 | 159.185 | C7H13NO3 | 98.000 | CCC[C@H](NC(C)=O)C(O)=O | 5g | 117563712
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STA PHARMACEUTICAL US LLC Fmoc-L-Val-L-Pro-OH | 50 g | CAS 109425-49-2 | MDL MFCD00237675
Fmoc-L-Val-L-Pro-OH is a Amino Acid reagent (Subcategory: Val) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 109425-49-2
- MDL: MFCD00237675
- InChIKey: PNFSGKNIZOXLKU-VXKWHMMOSA-N
- Molecular Weight: 436.508
- Molecular Formula: C25H28N2O5
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29339980
- Country Of Origin: China
- IUPAC: (((9H-fluoren-9-yl)methoxy)carbonyl)-L-valyl-L-proline
- SMILES: CC([C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(N4CCC[C@H]4C(O)=O)=O)C
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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STA PHARMACEUTICAL US LLC Fmoc-D-beta-HomoVal-OH | 10 g | CAS 266318-79-0 | MDL MFCD03095625
Fmoc-D-beta-HomoVal-OH is a Amino Acid reagent (Subcategory: Beta AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 266318-79-0
- MDL: MFCD03095625
- InChIKey: KFDMTAMWOIQTOB-IBGZPJMESA-N
- Molecular Weight: 353.418
- Molecular Formula: C21H23NO4
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-methylpentanoic acid
- SMILES: CC(C)[C@H](CC(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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